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Membrane permeability testing, Valia-Chien cells

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Membrane permeability testing, Valia-Chien cells

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Founded in 1973, PermeGear is recognized as a leader in the diffusion cell industry and continues to make hundreds of varieties of Franz cells, Side-Bi-Side cells, and In-Line cells. Custom diffusion cells are a specialty.

The Valia-Chien cell is a variety of Side-Bi-Side cell. It is generally the same as a Side-Bi-Side Cell except that the surfaces of the joint are not the ends of the heating jackets. The joint is like that of a Franz Cell with the joint’s halves being fused to the heating jackets. An additional clamp holds the membrane in place. Valia-Chien cells are ava...

Related literature


Founded in 1973, PermeGear is recognized as a leader in the diffusion cell industry and continues to make hundreds of varieties of Franz cells, Side-Bi-Side cells, and In-Line cells. Custom diffusion cells are a specialty.

The Valia-Chien cell is a variety of Side-Bi-Side cell. It is generally the same as a Side-Bi-Side Cell except that the surfaces of the joint are not the ends of the heating jackets. The joint is like that of a Franz Cell with the joint’s halves being fused to the heating jackets. An additional clamp holds the membrane in place. Valia-Chien cells are available with o-ring, flat ground o-ring, or flat flange joints.

The wrap around the cell clamp for a Valia-Chien cell is not the same as the cell clamp for a Side-Bi-Side cell: clamps for one variety of cell will not work properly with the other cells. There are also different stirrers for each kind of cell. For corneal work the Valia-Chien cell must be used because there is no practical option for a Side-Bi-Side cell to have a spherical surface.

If the heating jacket of a Side-Bi-Side cell is removed, the Side-Bi-Side cell becomes an unjacketed Valia-Chien cell. This is because the clamping can no longer be done with the wrap around Side-Bi-Side cell clamp which uses the heating jackets to hold Side-Bi-Side cell halves together. Instead a pinch clamp for flat ground o-ring and o-ring joints, or a horsehoe clamps for flat flange joints, does the clamping. Therefore, it you ask for a quotation for an unjacketed Side-Bi-Side cell, you will receive a quotation for an unjacketed Valia-Chien cell.

H-Series stirrers for Valia-Chien cells are available as 1-station, 3-station, or 9-station units. They come with cell clamps.
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Membrane permeability testing, Valia-Chien cells